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Medical Review REGEN scientific content was reviewed for accuracy on 2026-07-16 By Dr
The medium was replaced, and after 8 h the cell supernatant was collected and co-incubated with RAW264.7 cells for 4 h

For example, OTA induced strong down-regulation of regucalcin, which interferes with intracellular calcium regulation, a finding associated with nephrotoxic and nephrocarcinogenic compounds such as cisplatin [74,75]
