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Certain medications The following drugs can reduce levels of vitamin B12 in your body: Antibiotics -- long-term use can lower vitamin B levels generally Anti-seizure drugs Chemotherapy medicines, especially methotrexate Drugs used to reduce stomach acid, like H2 blockers (Pepcid AC, Tagamet, Zantac) and proton pump inhibitors (Nexium, Prevacid, Prilosec) Metformin (Glucophage) -- taken for diabetes Colchicine -- taken for gout Some cholesterol-lowering medications Other causes You're over 65

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General Wellness and Anti-Aging Protocol Dose: 0.5 to 1.5 mg per day Route: Subcutaneous Frequency: Daily or every other day Cycle: 30 days on, 30 days off Expected results: Improved skin quality, energy, and recovery over 4 to 8 weeks Best for: Maintenance, systemic anti-inflammatory support, preventive use This lower-dose protocol suits individuals who have completed a targeted cycle (skin, hair, or healing) and want to maintain results