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In mild cases, low levels of vitamin B12 can cause fatigue and anemia, while more serious deficiencies can lead to serious neurological and heart impairments

doi: 10.1139/gen-2020-0135 41 LucasCWongPKleinJCastroTBRSilvaJSundaramMet al

The most common is injecting too quickly, which creates a pocket of medication that absorbs slowly and forms a temporary nodule

A topical numbing cream can be applied prior to the injection if you need it
