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In addition to these actions, cacao modifies the growth of beneficial bacteria in the gut and as such influences the interaction between these gut microbes and the bodys own cells
Higher glutamate concentrations in the extracellular space could bind and signal through receptors to produce biological effects on the physiopathology of non-neural cells, independent of nervous system fibers

Moreover, many studies have shown a clear connection between IGF-1 deficiency and metabolic syndrome

Diabetes causes dysfunctional dopamine neurotransmission favoring nigrostriatal degeneration in mice
