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In some embodiments, the pharmaceutical compositions include other medicinal or pharmaceutical agents, carriers, adjuvants, such as preserving, stabilizing, wetting or emulsifying agents, solution promoters, salts for regulating the osmotic pressure, and/or buffers

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As shown in Figure 3, CYP2E1 not only metabolizes ethanol to acetaldehyde but also generates reactive oxygen species and hydroxyethyl radicals, which contribute to oxidative stress and potential liver damage (90)

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