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reported that in NSCLC patients, combining a PD-1 immune checkpoint inhibitor with erastin enhanced CD8+ T cell-mediated IFN secretion, downregulating SLC7A11 and reversing immune resistance, resulting in an improved objective response rate of 32% in a phase II clinical trial(NCT04205357) (323)

1,25(OH)2vitamin D3 stimulates myogenic differentiation by inhibiting cell proliferation and modulating the expression of promyogenic growth factors and myostatin in C2C12 skeletal muscle cells

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doi:10.1002/fsn3.4073