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First, chronic alcohol intake can inhibit TFEB expression while increasing the activity of the mTOR, thereby inhibiting autophagy

[DOI] [PMC free article] [PubMed] [Google Scholar] 22.Hirano S., Minamiguchi S., Yamashita M., Ohno T., Kanemaru S., Kitamura M

The data presented here demonstrate that the GSK3 inhibitors promoted the efficient up-regulation of definitive endoderm specific transcription factors GATA4, FOXA2, SOX17 and CXCR4

Every major claim carries an evidence grade
