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After exposure to oxidative stimuli, Nrf2 dissociates from Keap1, its negative regulator, and translocates into the nucleus where it heterodimerizes with small Maf proteins [77] and binds to antioxidant responsive element (ARE) sequences, triggering a cytoprotective adaptative response

Inorg Chem 46:20942104 Kasparkova J, Zehnulova J, Farrell N, Brabec V (2002) DNA interstrand cross-links of the novel antitumor trinuclear platinum complex BBR3464

Renoprotective effect of celecoxib against gentamicin-induced nephrotoxicity through suppressing NFB and caspase-3 signaling pathways in rats
