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In this context, impaired fertility and GSH conjugation were hypothesized as Adverse Outcome (AO) and Molecular Initiating Event (MIE), respectively, for this AOP
The central compartment consists of the plasma, extracellular fluids and highly perfused tissues in which drug equilibrate rapidly
In addition, the RGC deaths in these mice are distributed across the whole retina, rather than in specific regions as seen in human glaucoma
Each key latches onto a specific lock aka a receptor in the body, and unlocks a specific process like making collagen, repairing tissue, releasing a hormone, and so on," he adds
