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Also, it was proven that light-induced circadian disruption primed a heightened pro-inflammatory TNF response to LPS challenge, while immune imbalance, with increases in pro-inflammatory M1 macrophages and reductions in regulatory T cells, suggesting compromised anti-tumor immune surveillance 133,134

Representative Congo Red staining of frontal cortex sections from ( A ) male transgenic mouse treated with intranasal saline or ( B ) male transgenic mouse treated with intranasal GHK-Cu

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