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Moreover, GSTs can physically interact with various proteins and structurally diverse non-substrate molecules, including heme, steroids, and bilirubin, thereby impacting signaling pathways and altering their activity

Gottlieb SS, Fisher ML, Pressel MD, Patten RD, Weinberg M, Greenberg N (1993) Effects of intravenous magnesium sulfate on arrhythmias in patients with congestive heart failure

ACS Nano 8 , 51165124 (2014)

At 7 and 14 days after topping, leaf nicotine content in overexpression lines was increased by approximately 2540% relative to the wild type, whereas root nicotine content was reduced by approximately 1530% (mean SD, n = 3 biological replicates), indicating a substantial effect size in addition to statistical significance