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35 Metaanalyses of studies of serum carnitine and ammonia concentrations in patients treated with VPA showed that raised ammonia was associated with reduced Lcarnitine concentrations

Because BCAAs, such as valine, leucine, and isoleucine, are absorbed in the peripheral tissue, patients with cirrhosis have a lower concentration of the BCAAs and a higher concentration of the aromatic amino acids in the blood compared with healthy people

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