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The datasets were grouped so that a single state space model was used to capture all the responses (across time, concentration, and test material) for a single readout obtained within a particular study (laboratory/tissue model)
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Ipamorelin stimulates pulsatile GH secretion from anterior pituitary somatotrophs by acting at the ghrelin receptor (GHS-R1a) a distinct and mechanistically complementary pathway to the GHRH receptor pathway through which CJC-1295 No DAC and tesamorelin operate
doi: 10.3389/fendo.2012.00131 107 YangSYGoldspinkG
