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Description
The metabolism of the branched-chain amino acids is critical to overall nitrogen homeostasis in the brain and to the maintenance of proper levels of the excitatory neurotransmitter, glutamate

Arterial levels of oxidized glutathione (GSSG) reflect oxidant stress in vivo

A PDE6-KRas inhibitor chemotype with up to seven H-bonds and picomolar affinity that prevents efficient inhibitor release by Arl2

doi: 10.1038/nature08987
