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We have recently reported (Jahn, et al., 2016), using meta-analyses, that GSTZ1 is often misregulated in cancers, showing high mRNA expression in some organs in which the basal expression is low, including breast, and low expression in the liver, where GSTZ1 is expressed normally

The authors proposed a positive feedback mechanism where MACC1 acts as a transcriptional regulator of the gene
PRIMA-1, a mutant p53 reactivator, induces apoptosis and enhances chemotherapeutic cytotoxicity in pancreatic cancer cell lines
Suppression of acute and chronic rejection by hepatocyte growth factor in a murine model of cardiac transplantation: induction of tolerance and prevention of cardiac allograft vasculopathy
