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Author Contributions Literature searches and analyses were completed by D.M

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Retatrutide simultaneously activates GLP-1, GIP, and glucagon receptors, distinguishing it from licensed agents such as semaglutide or tirzepatide

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Results: Four patients (3 male, 1 female) with PLA2G6 mutations were identified

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The structure of the kumamolisin-As enzyme from the acidophilic bacterium Alicyclobacillus sendaiensis provided a starting point for engineering a gluten-degrading enzyme that is active in the acidic conditions of the stomach

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