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In intranasal delivery targeting the olfactory mucosa, overcoming the mucus barrier is the first challenge: drugs must dissolve in or traverse the mucus layer before encountering enzymatic degradation or mucociliary clearance (Rassu et al., 2018)

Psoriasis mostly appears as red, raised, scaly patches called plaques

Hypokalemia and thrombocytosis could occur upon conversion of severe megaloblastic anemia to normal erythropoiesis with methylcobalamin therapy

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