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Indeed, recent elegant studies in humans and collecting duct cell lines showed that IGF-1 regulates sodium reabsorption in the distal nephron by activation of the IGF-1R, which results in upregulation of the ENaC [25, 26]

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Therapy with the NL-GHK-Cu peptide allows for the restoration, maintenance, and protection of a properly functioning nervous system

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In addition, the lack of this enzyme exhibited a pronounced susceptibility to paraquat toxicity

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USA 72 , 10031006 (1975)

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