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The expression of OTUD5 was decreased in podocytes under high glucose stimulation

Several studies have reported that glucose-starvation activates gluconeogenesis for serine and glycine synthesis [53, 54]
Although glucocorticoids stimulate leptin release from adipose tissue, which would normally lead to appetite suppression, they also reduce the sensitivity of the brain to leptin, contributing to leptin resistance (Zakrzewska et al., 1997, 1999

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