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Together, these findings indicate that while strong oxidants, such as H 2 O 2 , favor irreversible thiol overoxidation and suppress disulfide chemistry, reactive nitrogen species provide a physiologically relevant pathway for disulphide cross-linking of TTR

ATP7A is expressed in various tissues and organs, whereas ATP7B is predominantly expressed in the liver, suggesting that ATP7A, but not ATP7B, is primarily involved in the exporting of copper into the brain cell (Lutsenko et al., 2007)

Value of measurable residual disease monitoring in patients with acute promyelocytic leukemia in the era of frontline 'chemotherapy-free' therapy

Specific combinations of ferroptosis inducers with conventional or immunotherapies, along with their synergistic mechanisms and efficacy, are detailed in Table 3