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In Fura-2 loaded rat myocytes, the dose-dependent (520 M) increase in cytosolic Ca 2+ acutely evoked by LCAC superfusion was significantly blunted with EGTA chelation of extracellular Ca 2+ ( 2+

21 The patient in the scenario above also was determined to have a previously undiagnosed OTC deficiency on her post-mortem exam
