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Description
527,528 Second-line medications Opioids and atypical opioids Tapentadol: A centrally acting analgesic with both opioid agonist and norepinephrine reuptake inhibition properties

patients receiving thyroid-hormone replacement or those with thyroid dysfunction should be monitored for changes in symptom control

Moderate deficiency : Injections every 2-3 months are often recommended

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