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Some studies suggest that NSAIDs can interfere with mitochondrial function, leading to an increase in reactive oxygen species (ROS)unstable molecules that contribute to oxidative stress

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These findings suggest that exploiting CHAC1 is potentially safe for TP53-mutant tumors

[DOI] [PubMed] [Google Scholar] 96.Chelliah MP, Zinn Z, Khuu P, Teng JMC