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Mistake #2: Skipping Inflammation Control and Expecting Regeneration Anyway Inflammation is not an enemy

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This decline can impair physical function and mobility

is that they have evolved as a result of a need for a higher regulatory input in Wnt signaling in the adult tissue stem cells frequently seen in long-lived vertebrates (Clevers et al., Lgr5 especially, has garnered much attention the last few years as a high fidelity marker of stem cells in several regenerating tissues (Schuijers and Clevers, 2012)
