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Mutations in the glucocerebrosidase gene are associated with early-onset Parkinson disease

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doi: 10.3389/fnins.2025.1559597 Received 29 January 2025 Accepted 05 March 2025 Published 19 March 2025 Volume 19 - 2025 Edited by Marcos Roberto De Oliveira, Federal University of Rio Grande do Sul, Brazil Reviewed by David Tattersall, GlaxoSmithKline, United States Serenella Medici, University of Sassari, Italy Updates Copyright 2025 Feng, Zhang, Liu, Wang, Dang, Han and Zhang

For example, inflammation affects neurotransmitter balance, increases free radical production, and reduces important proteins essential for the growth and plasticity of neurons