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Potential risks include unpredictable pharmacokinetic interactions, immunogenicity, injection site reactions, gastrointestinal adverse effects, and disruption of copper homeostasis
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(2006) have presented a newer model for the catalytic reaction in which Glu146 functions as a general base, accepting a proton from zinc-bound water and shuttling the proton to the leaving group facilitating breakdown of the tetrahedral intermediate
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Am J Physiol Gastrointest Liver Physiol 2009
