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Metformin enhances autophagy and normalizes mitochondrial function to alleviate aging-associated inflammation

From a systems perspective, anxiety disorders is characterized by abnormalities in neurotransmitter functions, neurotrophic signaling, the endocannabinoid system and HPA axis function and these alterations are further compounded by chronic inflammation and maladaptive immune responses (Cai et al., 2025)
doi: 10.1016/j.cmet.2019.03.014

Schroer KT, Biagini Myers JM, Ryan PH, LeMasters GK, Bernstein DI, Villareal M, et al
