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Description
Anti-Parkinson drugs like dopamine (DA) agonists, levodopa, carbidopa, monoamine oxidase type B inhibitors and anticholinergics are used to replace DA in the current treatment model
In summary, modulating the surface charge of nanoparticles can improve their ability to deliver drugs into the CNS via the endogenous transport mechanism of the BBB
After pre-incubation, media was replaced by new media containing 300 M H 2 O 2 , for 24 h 71, 72
Nonetheless, other biological processes such as metabolism [24] and oxidative stress [25] can take part in this crosstalk
