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GLP-1 agonists can reduce thirst signals alongside appetite signals

SIRT2 mediates NADH-induced increases in Nrf2, GCL, and glutathione by modulating Akt phosphorylation in PC12 cells

Thus, the extent to which allantoin acts as a direct reductant instead of an activator of plant antioxidant systems remains unclear

While these studies are groundbreaking for patients seeking answers, they are primarily observational