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CrossRef American Head and Neck Society Endocrine Surgery Section and International Thyroid Oncology Group consensus statement on mutational testing in thyroid cancer: Defining advanced thyroid cancer and its targeted treatment David C

The binding of NO to a ferrous heme in its subunit increases both catalytic rate and active site affinity for the substrate [37]

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92 At modest concentrations, NO exerts a protumorigenic response that may benefit tumor growth and survival
