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Mehasseb et al., 2009

This co-delivery mechanism enables a unique two-phase action: an immediate, potent radical hit confined to the near-field site of application, causing localized and often irreversible biomolecular damage, followed by a sustained, programmable non-radical afterglow that diffuses to modulate signaling pathways and inflammatory responses over a broader spatial and temporal range

Currently, the pathophysiology for kernicterus/hyperbilirubinemia-induced sensorineural hearing loss is unknown and only a few studies have explored the role of G6PD def in auditory disorders [31,32]

The endoplasmic reticulum: structure, function and response to cellular signaling