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Indeed, proline could be crucial for protein conformation, and its substitution in essential domains may be responsible for relevant enzyme or transporter dysfunction, and then for severe clinical manifestations of disease [4]

L-carnitine plays an important role in the translocation of acetyl moieties from the mitochondria to the cytoplasm for acetylcholine synthesis in neurones. Inazu, M and Matsumiya, T, [Physiological functions of carnitine and carnitine transporters in the central nervous system]. in Nihon Shinkew Seishen Yakurigaku Zasshi , Volume 28, Issue 3, June 2008, pp 113 - 120