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Treatment of bacterial spontaneous peritonitis About one third of patients with SBP develop renal dysfunction119 due to a rapidly progressive impairment in systemic hemodynamics as a consequence of activation of vasodilation systems by proinflammatory cytokines.101,120 These patients present worse outcomes including decreased survival.101 The first randomized study assessing the effect of albumin administration in renal function and mortality, in patients with SBP, was performed in 1999

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The clinical consequence ranges from local inflammation through to systemic hypersensitivity and antibody formation

Brown Norway rats that did not undergo any treatment (PQ or eye drops) were also included as a healthy untreated control group