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Furthermore, a phospholipase present in the cytoplasm, namely platelet-activating factor (PAF)-acetylhydrolase (II), specifically inhibits short-chain fatty acid oxidation, interfering with the cell's redox capacity and blocking the aggregation of oxidized phospholipids such as PAF

In particular, GRP significantly altered the community structure of the gut microbiota, increasing the abundance of Bacteroidetes and decreasing Firmicutes in comparison with the HFD group who did not consume GRP (Xu et al., 2020)

However, further studies are needed regarding the stability and toxicity of CDNSs and their in vivo degradation products (Lembo et al., 2013

Domingo, E