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That inhibiting -oxidation renders the ER more oxidizing suggests that the cell might be able to safely oxidize nutrients or nascent proteins, but not both simultaneously

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This is because melanin production resumes once glutathione levels drop in the body

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Jumnongprakhon P, Sivasinprasasn S, Govitrapong P, Tocharus C, Tocharus J

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doi: 10.1016/j.trecan.2017.01.005

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