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Luminescence was measured using a microplate reader (Tecan Reader M1000)

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Main conclusions: GHK-Cu acts via 6 main mechanisms (described above) The endogenous decrease with age is documented in various populations Topical applications in dermatology are the best validated Antimicrobial effect , GHK-Cu also has a mild antibacterial profile The safety profile is excellent, no toxic doses were reached in animal studies Why it matters: This review became a reference source for the dermatological and cosmetic research community

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doi: 10.1002/eji.202350823 40 SteffenUSchettGBozecA

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Non-Smad pathways in TGF- signaling

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