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More importantly, Pt-based tumor-targeting nanosystems and activatable nanosystems have broad prospects and huge potential in improving the therapeutic efficiency exclusively at tumor sites, while avoiding the possible toxic effect toward the peripheral nervous system

Keywords: glutathione, tumor therapy, tumor metabolism, nitrosoglutathione, S -nitrosation, ferroptosis, reactive oxygen species, metabolism modeling 1

Peri-operative chemotherapy with or without bevacizumab in operable oesophagogastric adenocarcinoma (UK medical research council ST03): primary analysis results of a multicentre, open-label, randomised phase 2-3 trial

Pradhananga, S., Wilkinson, I