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Likewise, RNA-sequencing analyses in postmortem human studies have yielded evidence of a downregulation of PPP3CA, which encodes for calcium-dependent calmodulin-stimulated protein phosphatase, in patients with CTE compared to healthy subjects, and these patterns were inversely correlated with phosphorylation of tau at Ser202/Thr205 (Seo et al., 2017)
176 SugiharaG.HashimotoK.IwataY.NakamuraK.TsujiiM.TsuchiyaK
refrigerate PEER-REVIEWED EVIDENCE Kraus D, Yang Q, Kong D, et al
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