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Therefore, the antioxidant species were used at different doses, so further clinical studies are needed to identify the minimum useful dose to be used as monotherapy or in combination with conventional therapies

3.5.2 Apoptosis inhibition In contrast, curcumin exhibits cytoprotective effects in non-cancerous contexts by suppressing UV-induced apoptosis at lower concentrations (0.110 M)

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Notably, the adverse effects caused by metformin therapy for adolescent patients with PCOS, especially gastrointestinal side effects, need to be a concern, as they may affect their quality of life and treatment adherence