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[DOI] [PubMed] [Google Scholar] 112.Siegrist-Kaiser CA, Pauli V, Juge-Aubry CE, Boss O, Pernin A, et al

Mechanisms of Ageing and Development, 124(1), 953957

Leptin and the LepR Ig domain then trans-interact to create the site 3 interface, which dimerizes LepR to produce signalling competent 2:2 complexes

While early human data is encouraging, comprehensive clinical trial data remains limited for most peptide compounds