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Cell Stem Cell 28 , 331342.e5 (2021)

Am J Med Genet B Neuropsychiatr Genet

Platelet activation, aggregation, and subsequent intra-arterial thrombosis are important steps in atherosclerotic thrombosis, and enhanced platelet reactivity is associated with the degree of terminal organ injury and poor prognosis ( 2+ release from intracellular stores ( in vivo can potentially lead to thrombosis, and within the physiological range of TMAO concentration observed in human and animal models, the effect of TMAO on platelet function is dose-dependent

Translational analyses were performed under the study ONCOBIOTICS (sponsor protocol no