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Elsby R, Kitteringham NR, Goldring CE, Lovatt CA, Chamberlain M, Henderson CJ et al

In particular, Phe286 6.58 and Phe290 6.62 , located at the entrance of the ligand-binding pocket, are thought to contribute to the accessibility of the acyl-modified peptide through their hydrophobic properties (You et al., 2023)

Mechanism of Action of Vitamin B12 on Neurotransmitters Vitamin B12 plays several important roles in the nervous system and its deficiency can lead to neurological symptoms and may contribute to the development of neurodegenerative diseases

In addition, the microglia themselves, which are involved in the phagocytosis of dead cells and pathogens, produce O 2 and NO when activated [87,88]