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In summary, the rationale of employing DMF in psoriasis consists in reducing cellular inflammation both by decreasing glutathione intracellular levels and by inducing a switch in immune response toward an anti-inflammatory/immunoregulatory setting (68, 69)

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Ma W, Wang Y, Liu J (2025) NLRP3 inflammasome activation in liver disorders: from molecular pathways to therapeutic strategies

Individuals with cystinuria or homocystinuria, those on chemotherapy, or taking certain medications should consult a provider before supplementing, as glutathione may interact with specific treatments