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Elevated Total Homocysteine in All Participants and Plasma Vitamin B12 Concentrations in Women Are Associated With All-Cause and Cardiovascular Mortality in the Very Old: The Newcastle 85+ Study

Without vitamin D, there could be an increase in inflammation that is the cause of sciatica

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Certain groups are at a higher risk of B12 deficiency, including the elderly because of reduced absorption due to decreased stomach acid