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This observation is confirmed by the increase in apparent K D -values of NBD-Sph from 120 to 210 nM as the edelfosine concentration was raised
Notably, at 100 g/ml concentration of Madhugrit the rate of migration and percentage of wound closure was equivalent to that of HaCaT cells kept in normal glucose (5.5 mM) condition ( Figures 6B, C )
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