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Methods: The 677CT and 1298AC mutations in the MTHFR gene were determined by either a laboratory-developed test involving PCR amplification and restriction digestion utilizing the ABI 3100 capillary electrophoresis apparatus (Applied Biosystems Inc) or by using an Analyte Specific Reagent (ASR) supplied by Third Wave Technologies
In aged tissue models, GHK-Cu administration increases epidermal thickness by 20%, enhances dermal collagen content by 70%, and improves elasticity markers by 27%
