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Consistent with our previous experimental design 27 , except for the WD and LD groups, which continued to drink normal water, the other groups were treated with dextran sodium sulfate (3% DSS, w/v) for 7 days after four weeks of diet and were gavaged (PBS, AR113, and AR113 bsh 1) on the 5th day of the DSS treatment, with the gavage process lasting for 8 days, and the whole experimental cycle totaled 40 days ( n = 8)

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