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The thyroid gland has the highest concentration of selenium in the body, which is predominantly stored in the thyrocytes in the form of selenoproteins, such as deiodinases, GPx, and thioredoxin reductases (181, 182)

This information can inform the design of biomaterials for ACL reconstruction that mimic the natural mechanical properties of the ligament, enhancing the success of surgical interventions

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Consequences that are especially detrimental to the proper functioning of the brain include mitochondrial dysfunction, altered neuronal signaling, and inhibition of neurogenesis [23]