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Sci Rep 11 , 17598 (2021)

doi:10.1046/j.1471-4159.2001.00101.x Hirsch-Reinshagen V, Zhou S, Burgess BL et al (2004) Deficiency of ABCA1 impairs apolipoprotein E metabolism in brain

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Surgery is preferable in patients with very large goitres and/or significant compressive symptoms and for those who do not want to have radiation therapy
