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Altogether, Pb disrupts not only the presence of essential docking and fusion proteins but also the underlying calcium-dependent signaling that coordinates precise vesicle release, contributing to long-lasting deficits in excitatory neurotransmission

Neuropathy and Nerve Damage in Diabetes Diabetic neuropathy, a common and debilitating complication of diabetes, stems largely from hyperglycemia-induced oxidative stress, which increases reactive oxygen species production and damages peripheral nerves [42]

MAD, MCTKD, and LGIT are generally less restrictive, more palatable, and easier to follow in the long term (52, 53)

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